Get our Twins vs. White Sox prediction for today. The Minnesota Twins (8–15) will host the Chicago White Sox (5–18) on Wednesday at Target Field, with first pitch scheduled for 7:40 p.m. ET. The game airs on MNNT and CHSN, and can be streamed live on FuboTV.
Minnesota enters the game as a heavy -271 moneyline favorite, while Chicago is listed at +220. The run total is set at 8.5 runs.
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📺 Where To Watch Twins vs. White Sox? (April 23, 2025)
- Date: Wednesday, April 23, 2025
- Time: 7:40 p.m. ET
- Location: Target Field, Minneapolis, MN
- TV: MNNT, CHSN
🔢 Twins vs. White Sox Betting Odds
| Market | Odds |
| Moneyline | Twins -271 / White Sox +220 |
| Run Line | Twins -1.5 |
| Total Runs | Over/Under 8.5 |
🧠 Betting Trends
🔹 Twins
- 7–9 when favored on the moneyline this season (43.8%)
- 8–12–3 over/under record
- Rank 26th in MLB with 3.4 runs/game
- .210 team batting average (29th in MLB)
- 3.93 ERA (13th-best in MLB)
🔸 White Sox
- 5–18 as underdogs (21.7%)
- 9–14 over/under record
- 3.1 runs/game (28th in MLB)
- League-worst .201 team batting average
- 4.27 team ERA (20th in MLB)
🧱 Starting Pitching Matchup
🟦 Twins – David Festa (0-0, 0.00 ERA)
- Third start of the season
- Last outing: 4.1 IP, 0 ER, 5 H, 6 K vs. Mets
- Opponents batting .235 against him
- 10 K/9, 1.11 WHIP in 9 innings
⚪ White Sox – Bryse Wilson (0-0, 4.50 ERA)
- First start of the season after 9 bullpen appearances
- Opponents hitting .320 against him
- 6.0 K/9, 2.3 BB/9
🔥 Recent Form
Minnesota
- 8 home runs in last 10 games
- .224 AVG and .350 SLG over last 10
- Buxton: 3 HR, 6 RBI in last 10 games
- Larnach: .300 OBP in last 10
Chicago
- 8 home runs in last 10 games
- .188 AVG and .294 SLG over last 10
- Luis Robert: 2 HR, 5 RBI in last 10
- Benintendi: 2 HR, .160 AVG in last 10
🧍 Players to Watch
⭐ Twins
- Byron Buxton – Leads the team with 4 HR, hitting .232
- Ty France – Team-best .238 AVG, 2 HR, 11 RBI
- Trevor Larnach – .200 AVG, 15 hits this season
⭐ White Sox
- Andrew Benintendi – 4 HR, .160 over last 10
- Luis Robert – Batting .151 with 2 HR, 12 BB
- Matt Thaiss – .222 AVG, 1 HR, 10 BB
🚑 Injury Report
Minnesota
- Royce Lewis (Hamstring) – 10-Day IL
- Pablo López (Hamstring) – 15-Day IL
- Michael Tonkin, Matt Wallner, Willi Castro – All sidelined
Chicago
- Tauchman, Slater, Meidroth, Lee – 10-Day IL
- Pérez, Bush, Thorpe, Scholtens – 60-Day IL
🎯 Top Player Prop Bets
Minnesota Twins:
- Byron Buxton Over 0.5 RBIs: Buxton has been a consistent run producer, and facing a struggling White Sox pitching staff increases his RBI potential.
- Trevor Larnach Over 0.5 Total Bases: Given his recent hitting streak and success against the White Sox, Larnach is a strong candidate to accumulate total bases.
Chicago White Sox:
- Andrew Benintendi Over 0.5 Singles: Benintendi has recorded a single in each of his last four road appearances against opponents with losing records.
- Andrew Vaughn Over 0.5 Hits: Vaughn has recorded at least one hit in each of his last six appearances against the Twins after playing the previous day.
🔁 Same-Game Parlay (SGP) Picks
Parlay Option 1:
- Twins -1.5 Run Line: Minnesota has dominated recent home games against Chicago, winning each of the last nine at Target Field following a win.
- Total Runs Under 8.5: Seven of the Twins’ last eight games against American League opponents have gone under the total runs line.
- Trevor Larnach to Record a Hit: Larnach is on a four-game hitting streak and has been productive against the White Sox at home.
Parlay Option 2:
- Twins to Lead After 5 Innings: Minnesota has led after five innings in each of their last five home games against AL Central opponents with losing records.
- Byron Buxton to Hit a Home Run: Buxton leads the Twins with four home runs this season and has been a key offensive contributor.
Bryse Wilson Under 4.5 Strikeouts: Wilson has a strikeout rate of just 8% when going through the lineup the first time in a game this season.
🎯 Final Twins vs. White Sox Prediction
- Score: Twins 5, White Sox 4
- Best Bets:
- ✅ Twins to win (-271)
- ✅ Over 8.5 runs
- ✅ Byron Buxton to record an RBI
- ✅ Luis Robert to hit a home run (+500 range)
With Festa dealing on the mound and Chicago’s offense in a slump, Minnesota should secure their second straight win. That said, Bryse Wilson has enough unpredictability to give up a couple of big innings—so expect a few runs late and a total over the 8.5 mark.
