Check Diamondbacks vs. Cubs prediction today. The Arizona Diamondbacks (11-7) roll into Wrigley Field on a four-game win streak as they take on the Chicago Cubs (12-9) in a Friday matinee. First pitch is set for 2:20 p.m. ET, with coverage on MARQ and ARID.
Arizona sends Corbin Burnes to the mound while the Cubs counter with Colin Rea in Game 1 of this three-game set. With a red-hot offense and elite contact rate, the Diamondbacks are narrow -133 moneyline favorites as they look to cool down MLB’s highest-scoring team.
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📺 Where To Watch Diamondbacks vs. Cubs? (April 18, 2025)
| Detail | Info |
| Date | Friday, April 18, 2025 |
| Time | 2:20 p.m. ET |
| Location | Wrigley Field, Chicago, IL |
| TV | MARQ, ARID |
💸 Betting Odds
| Bet Type | Line |
| Moneyline | Diamondbacks -133, Cubs +113 |
| Run Line | Diamondbacks -1.5 |
| Total Runs | 9.5 |
🔥 Pitcher Matchup
Corbin Burnes – Diamondbacks
- Record: 0-1
- ERA: 5.28
- IP: 15.1
- SO: 14
- WHIP: —
- Last Start: April 12 vs. Brewers – Win
Colin Rea – Cubs
- Record: 1-0
- ERA: — (no data provided beyond wins)
- Starts: 1
- Last Start: April 13 vs. Dodgers – Win (4-2)
📈 Betting Trends
- Arizona is 9-6 as the moneyline favorite this season, including 5-3 at -133 or shorter.
- Chicago is 5-7 as an underdog this year, with a 2-5 record at +113 or longer.
- The Diamondbacks are 7-8-3 O/U, while the Cubs are 13-8 O/U.
- Arizona has won 6 of their last 10, while Chicago has gone 5-5.
🧢 Team Insights
Diamondbacks
- Runs/Game: 5.4 (4th MLB)
- Home Runs: 24 (5th)
- Team AVG: .259 (4th)
- Strikeouts/Game: 6.8 (2nd best)
- ERA: 4.19 (21st)
Cubs
- Runs/Game: 5.9 (1st MLB)
- Home Runs: 27 (4th)
- Team AVG: .255 (7th)
- Strikeouts/Game: 8.1 (24th)
- ERA: 4.14 (18th)
🔍 Players to Watch
Diamondbacks
- Corbin Carroll: .329 AVG, 6 HR, 16 RBI
- Batting .381 with 10 RBI over last 10 games
- Josh Naylor: .328 AVG, 3 HR, 9 BB
- Geraldo Perdomo: .311 AVG, 16 RBI
- Eugenio Suarez: 5 HR, .159 AVG, .444 SLG
Cubs
- Kyle Tucker: 5 HR, 19 RBI
- Carson Kelly: .407 AVG, 4 HR, 11 BB
- Pete Crow-Armstrong: .259 AVG, 6 doubles, 3 HR
- Seiya Suzuki: .290 AVG, 4 HR, .377 OBP
📊 Head-to-Head (2025 Season)
| Date | Result |
| 3/30/25 | Diamondbacks 10-6 |
| 3/29/25 | Cubs 4-3 |
| 3/28/25 | Diamondbacks 8-1 |
| 3/27/25 | Cubs 10-6 |
Series tied 2-2 this season.
💰 ClutchBuzz Parlay of the Day
3-Leg Parlay Pick:
- Diamondbacks ML (-133)
- Under 9.5 Total Runs
- Corbin Carroll Over 1.5 Total Bases
💸 Estimated Odds: +525
🧾 Top Prop Bets
| Player | Prop | Odds (Est.) |
| Corbin Carroll | Over 1.5 TB | +100 |
| Josh Naylor | To Record an RBI | +150 |
| Carson Kelly | To Hit a Home Run | +350 |
| Kyle Tucker | Over 0.5 RBI | +135 |
🧠 Clutch Diamondbacks vs. Cubs Prediction
While Arizona enters on a four-game heater, the Cubs boast MLB’s most dangerous offense. If Burnes stumbles again, it could be costly — but Arizona’s high-contact lineup is built to do damage early. This one shapes up to be a grind.
Final Score Prediction: Cubs 4, Diamondbacks 3
Total Prediction: Under 9.5 Runs
